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ISIS - As of  12/12/19, 10:35:09 PM:   786 Insider Transactions.

Sector: Healthcare    Industry: Drug Manufacturers - Other
Prev Close:$57.56  Avg Vol(3m): 1,722,070  P/E: 483.70  EPS: 0.12

Email this page to a friend.    Institutional Transactions for ISIS

                Buy: Blue    Sell: Red
Non-meaningful transactions (gifts, grants, etc.) are automatically filtered out for quicker actions.
Buy(P) /
Sell(S)
P/S date Filed Date Company Symbol Insider Relationship Share Amt. Unit Price Total Proceeds Shares Owned Return(1m) Details
S 2015-12-16 2015-12-17 19:24:37.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 3,909 $58.85 $230,045.00 7,316 N/A view
S 2015-12-15 2015-12-17 19:24:37.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 4,000 $56.00 $224,000.00 7,316 N/A view
S 2015-12-01 2015-12-02 18:59:04.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,000 $61.50 $61,500.00 6,259 N/A view
S 2015-11-10 2015-11-12 19:03:55.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 5,000 $64.00 $320,000.00 7,316 N/A view
S 2015-11-11 2015-11-12 19:03:20.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 3,125 $64.18 $200,561.00 5,543 N/A view
S 2015-11-11 2015-11-12 19:03:20.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 3,750 $64.18 $240,673.00 5,543 N/A view
S 2015-11-06 2015-11-09 19:29:00.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 5,000 $56.00 $280,000.00 7,316 N/A view
S 2015-11-03 2015-11-04 19:00:36.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,000 $51.95 $51,950.00 6,259 N/A view
S 2015-10-23 2015-10-23 19:44:02.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 500 $45.30 $22,650.00 1,297 N/A view
S 2015-10-23 2015-10-23 19:44:02.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 2,000 $44.17 $88,350.00 1,297 N/A view
S 2015-10-23 2015-10-23 19:44:02.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 5,000 $45.30 $226,500.00 14,642 N/A view
S 2015-10-23 2015-10-23 19:44:02.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 15,837 $44.17 $699,600.00 14,642 N/A view
S 2015-10-23 2015-10-23 19:44:02.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 4,163 $43.90 $182,756.00 14,642 N/A view
S 2015-10-21 2015-10-23 19:44:02.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 500 $43.00 $21,500.00 1,297 N/A view
S 2015-10-21 2015-10-23 19:44:02.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,000 $43.00 $43,000.00 1,297 N/A view
S 2015-10-21 2015-10-23 19:44:02.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 15,000 $43.00 $645,000.00 14,642 N/A view
S 2015-10-02 2015-10-05 19:14:49.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 3,436 $42.39 $145,667.00 8,143 N/A view
S 2015-10-02 2015-10-05 19:14:49.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 2,000 $40.10 $80,200.00 8,143 N/A view
S 2015-10-01 2015-10-05 19:14:49.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 2,838 $40.13 $113,877.00 8,143 N/A view
S 2015-10-01 2015-10-05 19:14:49.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 4,162 $40.13 $167,003.00 8,143 N/A view
S 2015-07-06 2015-07-08 17:55:58.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 4,843 $57.01 $276,085.00 8,143 N/A view
S 2015-07-06 2015-07-08 17:55:58.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 1,375 $57.01 $78,384.60 8,143 N/A view
S 2015-07-06 2015-07-08 17:55:10.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,175 $57.01 $66,983.20 1,297 N/A view
S 2015-07-06 2015-07-08 17:55:10.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 5,000 $57.01 $285,035.00 14,642 N/A view
S 2015-07-02 2015-07-02 18:14:04.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 198 $56.30 $11,147.40 4,355 N/A view
S 2015-07-01 2015-07-02 18:06:58.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 6,218 $57.56 $357,914.00 8,143 N/A view
S 2015-07-01 2015-07-02 18:03:31.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,175 $57.56 $67,634.20 1,297 N/A view
S 2015-07-01 2015-07-02 18:03:31.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 5,000 $57.56 $287,805.00 14,642 N/A view
S 2015-06-08 2015-06-10 18:37:08.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 7,600 $66.22 $503,280.00 4,426 N/A view
S 2015-06-01 2015-06-03 17:29:55.0 ISIS PHARMACEUTICALS INC ISIS MUTO FREDERICK T director 10,000 $66.91 $669,110.00 1,095 N/A view
S 2015-04-07 2015-04-08 17:13:22.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 5,565 $63.07 $350,990.00 8,072 N/A view
S 2015-04-07 2015-04-08 17:12:28.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 2,034 $63.07 $128,286.00 1,297 N/A view
S 2015-04-07 2015-04-08 17:12:28.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 20,343 $63.07 $1,283,050.00 14,642 N/A view
S 2015-04-01 2015-04-06 11:59:02.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,966 $61.93 $121,759.00 1,297 5.96% view
S 2015-04-01 2015-04-06 11:59:02.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 19,657 $61.93 $1,217,400.00 14,642 5.96% view
S 2015-04-01 2015-04-06 11:52:25.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 5,377 $61.93 $333,009.00 8,072 5.96% view
S 2015-03-24 2015-03-25 16:24:10.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 9,000 $71.01 $639,090.00 7,229 6.53% view
S 2015-03-23 2015-03-25 16:24:10.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 1,000 $71.00 $71,000.00 7,229 4.58% view
S 2015-03-23 2015-03-25 16:24:10.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 5,000 $69.80 $349,020.00 7,229 2.94% view
S 2015-03-19 2015-03-20 18:59:20.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 10,000 $73.33 $733,260.00 3,387 10.90% view
S 2015-03-19 2015-03-20 18:59:03.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 8,000 $75.00 $600,032.00 4,555 12.90% view
S 2015-03-18 2015-03-20 18:58:28.0 ISIS PHARMACEUTICALS INC ISIS WENDER JOSEPH H director 6,400 $71.84 $459,804.00 30,217 9.07% view
S 2015-03-18 2015-03-20 18:58:28.0 ISIS PHARMACEUTICALS INC ISIS WENDER JOSEPH H director 6,100 $70.95 $432,783.00 30,217 7.92% view
S 2015-03-19 2015-03-20 18:56:34.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 10,525 $75.00 $789,417.00 6,174 12.90% view
S 2015-03-19 2015-03-20 18:56:34.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 2,600 $74.77 $194,394.00 6,174 12.62% view
S 2015-03-19 2015-03-20 18:56:34.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 4,000 $74.77 $299,068.00 6,174 12.62% view
S 2015-03-19 2015-03-20 18:56:34.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 6,100 $74.77 $456,079.00 6,174 12.62% view
S 2015-03-19 2015-03-20 18:56:34.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 5,683 $74.77 $424,901.00 6,174 12.62% view
S 2015-03-19 2015-03-20 18:56:34.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,617 $74.77 $120,898.00 6,174 12.62% view
S 2015-03-05 2015-03-09 19:46:22.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 7,000 $70.32 $492,226.00 4,555 12.36% view
S 2015-03-05 2015-03-09 19:46:22.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 8,000 $71.67 $573,344.00 4,555 14.01% view
S 2015-03-05 2015-03-09 19:46:22.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 80 $71.67 $5,733.44 4,555 14.01% view
S 2015-03-05 2015-03-09 19:46:22.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 3,015 $71.67 $216,079.00 4,555 14.01% view
S 2015-03-05 2015-03-09 19:28:36.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 7,437 $71.32 $530,377.00 3,387 13.58% view
S 2015-03-05 2015-03-09 19:28:36.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 8,000 $71.67 $573,344.00 3,387 14.01% view
S 2015-03-05 2015-03-09 19:28:36.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 12,657 $71.67 $907,102.00 3,387 14.01% view
S 2015-03-05 2015-03-09 19:28:00.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 4,133 $71.67 $296,204.00 6,174 14.01% view
S 2015-03-05 2015-03-09 19:28:00.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,667 $71.67 $119,471.00 6,174 14.01% view
S 2015-03-05 2015-03-09 19:27:04.0 ISIS PHARMACEUTICALS INC ISIS WENDER JOSEPH H director 12,500 $71.61 $895,174.00 30,217 13.94% view
S 2015-03-05 2015-03-09 19:26:24.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 7,000 $70.95 $496,682.00 4,095 13.14% view
S 2015-03-02 2015-03-04 19:16:33.0 ISIS PHARMACEUTICALS INC ISIS WENDER JOSEPH H director 7,000 $65.97 $461,785.00 30,217 6.58% view
S 2015-02-12 2015-02-17 17:40:00.0 ISIS PHARMACEUTICALS INC ISIS WENDER JOSEPH H director 10,000 $62.15 $621,460.00 37,217 -13.60% view
S 2015-01-27 2015-01-29 19:03:41.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,000 $72.93 $72,926.00 1,297 5.99% view
S 2015-01-27 2015-01-29 19:03:41.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $72.93 $729,260.00 14,642 5.99% view
S 2015-01-16 2015-01-20 20:00:50.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 136 $67.96 $9,243.10 1,297 6.04% view
S 2015-01-16 2015-01-20 20:00:50.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 160 $67.96 $10,874.20 1,079 6.04% view
S 2015-01-16 2015-01-20 20:00:50.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 121 $67.96 $8,223.64 822 6.04% view
S 2015-01-16 2015-01-20 20:00:50.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 4,130 $67.96 $280,693.00 14,642 6.04% view
S 2015-01-16 2015-01-20 20:00:50.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 2,933 $67.96 $199,338.00 10,959 6.04% view
S 2015-01-16 2015-01-20 20:00:50.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,574 $67.96 $106,975.00 8,344 6.04% view
S 2015-01-16 2015-01-20 19:59:29.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 1,818 $67.96 $123,559.00 8,072 6.04% view
S 2015-01-16 2015-01-20 19:59:29.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 1,372 $67.96 $93,246.60 6,452 6.04% view
S 2015-01-16 2015-01-20 19:59:29.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 903 $67.96 $61,371.50 5,229 6.04% view
S 2015-01-16 2015-01-20 19:58:39.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 714 $67.96 $48,526.30 4,426 6.04% view
S 2015-01-16 2015-01-20 19:58:39.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 539 $67.96 $36,632.60 3,265 6.04% view
S 2015-01-16 2015-01-20 19:58:39.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 80 $67.96 $5,437.12 2,389 6.04% view
S 2015-01-16 2015-01-20 19:58:39.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 201 $67.96 $13,660.80 2,261 6.04% view
S 2015-01-16 2015-01-20 19:58:09.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 714 $67.96 $48,526.30 3,387 6.04% view
S 2015-01-16 2015-01-20 19:58:09.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 250 $67.96 $16,991.00 2,226 6.04% view
S 2015-01-16 2015-01-20 19:58:09.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 120 $67.96 $8,155.68 1,822 6.04% view
S 2015-01-16 2015-01-20 19:58:09.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 207 $67.96 $14,068.50 1,629 6.04% view
S 2015-01-16 2015-01-20 19:57:28.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 714 $67.96 $48,526.30 6,174 6.04% view
S 2015-01-16 2015-01-20 19:57:28.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 250 $67.96 $16,991.00 5,013 6.04% view
S 2015-01-16 2015-01-20 19:57:28.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 120 $67.96 $8,155.68 4,609 6.04% view
S 2015-01-16 2015-01-20 19:57:28.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 207 $67.96 $14,068.50 4,416 6.04% view
S 2015-01-16 2015-01-20 19:55:55.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 714 $67.96 $48,526.30 7,229 6.04% view
S 2015-01-16 2015-01-20 19:55:55.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 539 $67.96 $36,632.60 6,068 6.04% view
S 2015-01-16 2015-01-20 19:55:55.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 265 $67.96 $18,010.50 5,192 6.04% view
S 2015-01-16 2015-01-20 19:54:22.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 714 $67.96 $48,526.30 7,570 6.04% view
S 2015-01-16 2015-01-20 19:54:22.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 533 $67.96 $36,224.80 6,409 6.04% view
S 2015-01-16 2015-01-20 19:54:22.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 296 $67.96 $20,117.30 5,544 6.04% view
S 2015-01-09 2015-01-13 18:51:55.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,000 $73.57 $73,570.00 627 20.04% view
S 2015-01-09 2015-01-13 18:51:55.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $73.57 $735,700.00 6,941 20.04% view
S 2015-01-12 2015-01-13 18:50:28.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 597 $73.10 $43,640.70 5,064 12.04% view
S 2015-01-07 2015-01-08 19:15:37.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,000 $68.05 $68,048.00 627 13.28% view
S 2015-01-07 2015-01-08 19:15:37.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $68.05 $680,480.00 6,941 13.28% view
S 2015-01-06 2015-01-08 19:15:37.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,000 $66.04 $66,038.00 627 10.64% view
S 2015-01-06 2015-01-08 19:15:37.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $66.04 $660,380.00 6,941 10.64% view
S 2015-01-02 2015-01-05 20:05:25.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 11,200 $62.12 $695,688.00 4,417 -10.55% view
S 2015-01-02 2015-01-05 20:04:26.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 283 $62.12 $17,578.50 4,082 -10.55% view
S 2015-01-02 2015-01-05 20:04:26.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,217 $62.12 $75,594.00 4,082 -10.55% view
S 2015-01-02 2015-01-05 19:56:54.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 76 $62.75 $4,769.00 1,935 -9.43% view
S 2014-12-01 2014-12-03 19:28:34.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 500 $50.37 $25,185.00 3,753 -22.57% view
S 2014-12-01 2014-12-03 19:28:34.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 500 $51.05 $25,525.00 3,753 -20.94% view
S 2014-12-01 2014-12-03 19:28:34.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 500 $52.21 $26,105.00 3,753 -18.25% view
S 2014-11-03 2014-11-05 18:08:06.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,500 $46.17 $69,255.00 3,753 -16.11% view
S 2014-10-30 2014-10-31 18:05:37.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 8,561 $45.12 $386,281.00 4,306 -14.78% view
S 2014-10-30 2014-10-31 18:05:37.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 2,510 $45.12 $113,254.00 4,306 -14.78% view
S 2014-10-23 2014-10-24 16:58:39.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,600 $42.22 $67,552.00 627 -20.65% view
S 2014-10-23 2014-10-24 16:58:39.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $42.22 $422,200.00 6,941 -20.65% view
S 2014-10-23 2014-10-24 16:58:39.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 3,000 $42.22 $126,660.00 6,941 -20.65% view
S 2014-10-03 2014-10-03 19:14:07.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,000 $39.49 $39,487.00 627 -16.32% view
S 2014-10-03 2014-10-03 19:14:07.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 13,000 $39.49 $513,331.00 6,941 -16.32% view
S 2014-10-01 2014-10-03 19:14:07.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 800 $37.91 $30,328.80 627 -21.50% view
S 2014-10-01 2014-10-03 19:14:07.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,200 $37.91 $45,493.20 627 -21.50% view
S 2014-10-01 2014-10-03 19:14:07.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 20,000 $37.91 $758,220.00 6,941 -21.50% view
S 2014-10-01 2014-10-03 19:06:39.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 800 $37.90 $30,320.00 3,753 -21.53% view
S 2014-10-01 2014-10-03 19:06:39.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 467 $38.20 $17,839.40 3,753 -20.58% view
S 2014-10-01 2014-10-03 19:06:39.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 233 $38.20 $8,900.60 3,753 -20.58% view
S 2014-09-02 2014-09-04 19:14:21.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 700 $40.60 $28,420.00 3,753 5.30% view
S 2014-09-02 2014-09-04 19:14:21.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 800 $40.30 $32,240.00 3,753 4.59% view
S 2014-08-27 2014-08-28 18:49:54.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 2,000 $40.55 $81,100.00 4,627 1.53% view
S 2014-08-27 2014-08-28 18:49:54.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 1,000 $40.53 $40,530.00 4,627 1.48% view
S 2014-08-27 2014-08-28 18:49:54.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 2,000 $40.50 $81,000.00 4,627 1.41% view
S 2014-08-26 2014-08-28 18:49:20.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 10,000 $38.14 $381,440.00 1,813 -4.68% view
S 2014-08-26 2014-08-28 18:49:20.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 15,000 $38.14 $572,160.00 1,813 -4.68% view
S 2014-08-26 2014-08-28 18:49:20.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 2,344 $38.14 $89,409.50 1,813 -4.68% view
S 2014-08-13 2014-08-15 18:39:51.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 1,600 $35.45 $56,726.40 627 -16.46% view
S 2014-08-13 2014-08-15 18:39:51.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 15,500 $35.45 $549,537.00 6,941 -16.46% view
S 2014-08-12 2014-08-12 18:51:39.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 800 $35.00 $28,000.00 3,753 -17.97% view
S 2014-08-11 2014-08-12 18:51:39.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 700 $35.00 $24,500.00 3,753 -16.77% view
S 2014-08-01 2014-08-01 19:45:10.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 1,000 $30.52 $30,525.00 627 -33.53% view
S 2014-08-01 2014-08-01 19:45:10.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 15,000 $30.52 $457,875.00 6,941 -33.53% view
S 2014-07-31 2014-08-01 19:17:25.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 79 $31.50 $2,488.50 1,813 -29.40% view
S 2014-07-01 2014-07-02 16:10:26.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,500 $35.33 $52,999.90 3,753 13.96% view
S 2014-07-01 2014-07-02 16:09:24.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,800 $35.55 $63,990.00 627 14.49% view
S 2014-07-01 2014-07-02 16:09:24.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 200 $35.55 $7,110.00 627 14.49% view
S 2014-07-01 2014-07-02 16:09:24.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 15,500 $35.58 $551,459.00 6,941 14.55% view
S 2014-07-02 2014-07-02 16:09:05.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 164 $35.95 $5,895.80 5,388 15.44% view
S 2014-06-23 2014-06-25 19:48:12.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 5,000 $36.54 $182,715.00 4,336 14.10% view
S 2014-06-23 2014-06-25 19:48:12.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 6,200 $36.97 $229,195.00 4,336 15.09% view
S 2014-06-19 2014-06-20 16:14:57.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 11,000 $35.10 $386,111.00 6,941 18.12% view
S 2014-06-16 2014-06-18 19:06:58.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 100 $35.27 $3,527.00 3,350 18.37% view
S 2014-06-16 2014-06-18 19:06:58.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 100 $35.25 $3,525.25 3,350 18.33% view
S 2014-06-16 2014-06-18 19:06:58.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 400 $35.02 $14,008.00 3,350 17.79% view
S 2014-06-16 2014-06-18 19:06:58.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 200 $35.25 $7,050.00 3,350 18.33% view
S 2014-06-10 2014-06-12 18:44:16.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 1,000 $33.46 $33,455.00 627 9.40% view
S 2014-06-10 2014-06-12 18:44:16.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 10,000 $33.46 $334,550.00 6,941 9.40% view
S 2014-04-02 2014-04-04 19:24:42.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 1,800 $43.65 $78,566.40 627 40.73% view
S 2014-04-02 2014-04-04 19:24:42.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 7,000 $43.65 $305,536.00 6,941 40.73% view
S 2014-03-03 2014-03-05 18:55:36.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 800 $50.70 $40,560.00 3,350 21.95% view
S 2014-03-03 2014-03-05 18:55:36.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 330 $49.20 $16,236.00 3,350 19.57% view
S 2014-03-03 2014-03-05 18:55:36.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 370 $49.20 $18,204.00 3,350 19.57% view
S 2014-02-03 2014-02-05 19:31:21.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,500 $50.45 $75,676.50 3,350 -0.85% view
S 2014-02-03 2014-02-05 19:30:38.0 ISIS PHARMACEUTICALS INC ISIS WENDER JOSEPH H director 4,700 $48.78 $229,278.00 31,135 -4.30% view
S 2014-01-30 2014-01-31 19:34:50.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 15,875 $50.36 $799,528.00 4,022 -1.26% view
S 2014-01-30 2014-01-31 19:34:50.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 23,635 $50.36 $1,190,350.00 4,022 -1.26% view
S 2014-01-29 2014-01-31 19:34:50.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 5,000 $48.81 $244,035.00 0 -4.49% view
S 2014-01-29 2014-01-31 19:34:50.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 5,000 $48.81 $244,035.00 0 -4.49% view
S 2014-01-29 2014-01-31 19:34:50.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 5,000 $48.81 $244,035.00 0 -4.49% view
S 2014-01-29 2014-01-31 19:34:50.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 31,028 $48.81 $1,514,380.00 4,022 -4.49% view
S 2014-01-29 2014-01-31 19:34:50.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 3,972 $48.81 $193,861.00 4,022 -4.49% view
S 2014-01-24 2014-01-24 20:26:43.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 2,813 $48.61 $136,740.00 2,313 -20.04% view
S 2014-01-24 2014-01-24 20:26:43.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 7,500 $48.68 $365,098.00 2,313 -19.87% view
S 2014-01-22 2014-01-24 20:08:17.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 13,900 $50.05 $695,639.00 4,955 -17.89% view
S 2014-01-22 2014-01-24 20:08:17.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 8,300 $50.05 $415,382.00 4,955 -17.89% view
S 2014-01-22 2014-01-24 20:07:04.0 ISIS PHARMACEUTICALS INC ISIS WENDER JOSEPH H director 10,000 $50.98 $509,803.00 31,135 -15.73% view
S 2014-01-16 2014-01-17 19:42:25.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 265 $47.08 $12,476.50 4,336 -10.79% view
S 2014-01-16 2014-01-17 19:42:25.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 539 $47.08 $25,376.70 3,906 -10.79% view
S 2014-01-16 2014-01-17 19:41:51.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 533 $47.08 $25,094.30 4,955 -10.79% view
S 2014-01-16 2014-01-17 19:41:51.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 296 $47.08 $13,936.10 4,090 -10.79% view
S 2014-01-16 2014-01-17 19:41:09.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 120 $47.08 $5,649.55 1,232 -10.79% view
S 2014-01-16 2014-01-17 19:41:09.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 207 $47.08 $9,745.58 1,039 -10.79% view
S 2014-01-16 2014-01-17 19:41:09.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 250 $47.08 $11,769.90 704 -10.79% view
S 2014-01-16 2014-01-17 19:40:00.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 202 $47.08 $9,510.18 1,816 -10.79% view
S 2014-01-16 2014-01-17 19:40:00.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 80 $47.08 $3,766.46 1,490 -10.79% view
S 2014-01-16 2014-01-17 19:40:00.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 539 $47.08 $25,376.10 1,362 -10.79% view
S 2014-01-16 2014-01-17 19:39:07.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 988 $47.08 $46,517.60 4,022 -10.78% view
S 2014-01-16 2014-01-17 19:39:07.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 653 $47.08 $30,744.70 2,415 -10.78% view
S 2014-01-16 2014-01-17 19:38:26.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 121 $47.08 $5,696.76 627 -10.79% view
S 2014-01-16 2014-01-17 19:38:26.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 160 $47.08 $7,532.78 431 -10.79% view
S 2014-01-16 2014-01-17 19:38:26.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,134 $47.08 $53,390.00 6,941 -10.79% view
S 2014-01-16 2014-01-17 19:38:26.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 2,112 $47.08 $99,435.50 5,097 -10.79% view
S 2014-01-08 2014-01-10 19:24:44.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 1,500 $40.05 $60,078.00 174 -22.57% view
S 2014-01-08 2014-01-10 19:24:44.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 11,000 $40.05 $440,572.00 1,661 -22.57% view
S 2014-01-08 2014-01-08 19:40:43.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 7,600 $42.02 $319,352.00 3,610 -16.83% view
S 2014-01-06 2014-01-08 19:40:43.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 7,400 $38.83 $287,364.00 3,610 -19.72% view
S 2014-01-02 2014-01-03 19:59:17.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 362 $39.25 $14,209.60 486 -30.08% view
S 2014-01-02 2014-01-03 19:47:23.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 2,500 $39.25 $98,132.50 174 -30.08% view
S 2014-01-02 2014-01-03 19:47:23.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 4,000 $40.00 $160,000.00 1,661 -27.65% view
S 2014-01-02 2014-01-03 19:47:23.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President and CEO) 25,000 $39.25 $981,325.00 1,661 -30.08% view
S 2013-12-26 2013-12-30 18:30:29.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 37,811 $40.91 $1,546,770.00 956 -18.36% view
S 2013-12-24 2013-12-24 15:22:07.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 20,000 $41.00 $819,920.00 956 -18.11% view
S 2013-12-23 2013-12-24 15:22:07.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 1,771 $41.68 $73,817.10 956 -20.37% view
S 2013-12-23 2013-12-24 15:22:07.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 48,229 $41.68 $2,010,230.00 956 -20.37% view
S 2013-12-20 2013-12-20 21:28:01.0 ISIS PHARMACEUTICALS INC ISIS WENDER JOSEPH H director 10,000 $40.01 $400,125.00 41,135 -17.81% view
S 2013-12-19 2013-12-20 21:28:01.0 ISIS PHARMACEUTICALS INC ISIS WENDER JOSEPH H director 9,731 $39.13 $380,813.00 51,135 -20.46% view
S 2013-11-26 2013-11-27 16:42:00.0 ISIS PHARMACEUTICALS INC ISIS WENDER JOSEPH H director 10,000 $36.63 $366,336.00 45,866 -11.84% view
S 2013-11-25 2013-11-27 16:40:54.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 6,000 $36.86 $221,156.00 2,313 -10.53% view
S 2013-09-20 2013-09-23 19:39:54.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 8,740 $35.90 $313,749.00 1,661 8.96% view
S 2013-09-19 2013-09-23 19:39:54.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 30,000 $35.02 $1,050,600.00 1,661 6.68% view
S 2013-09-19 2013-09-23 19:39:54.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 20,000 $35.12 $702,480.00 1,661 6.96% view
S 2013-09-20 2013-09-23 19:39:01.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 10,000 $35.90 $358,980.00 956 8.96% view
S 2013-09-20 2013-09-23 19:39:01.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 30,000 $35.90 $1,076,940.00 956 8.96% view
S 2013-09-19 2013-09-23 19:39:01.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 30,000 $35.02 $1,050,600.00 956 6.68% view
S 2013-09-19 2013-09-23 19:39:01.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO & Secretary) 20,000 $35.12 $702,480.00 956 6.96% view
S 2013-09-20 2013-09-23 19:38:19.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 18,281 $35.89 $656,105.00 769 8.94% view
S 2013-09-19 2013-09-23 19:38:19.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 1,875 $33.35 $62,531.20 769 2.01% view
S 2013-09-19 2013-09-23 19:38:19.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 22,500 $33.35 $750,375.00 769 2.01% view
S 2013-09-19 2013-09-23 19:38:19.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 5,000 $33.35 $166,750.00 769 2.01% view
S 2013-09-19 2013-09-23 19:38:19.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 625 $33.35 $20,843.80 769 2.01% view
S 2013-09-19 2013-09-23 19:38:19.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 20,000 $33.96 $679,200.00 769 3.77% view
S 2013-09-19 2013-09-23 19:37:28.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 10,000 $35.02 $350,200.00 2,866 6.68% view
S 2013-09-11 2013-09-11 19:27:51.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (COO, President) 20,000 $31.18 $623,620.00 725,391 -4.36% view
S 2013-09-10 2013-09-11 19:27:51.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (COO, President) 30,000 $31.65 $949,440.00 745,391 -5.50% view
S 2013-09-09 2013-09-11 19:27:51.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (COO, President) 26,615 $30.42 $809,495.00 1,661 -6.00% view
S 2013-09-09 2013-09-11 19:27:18.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 10,000 $30.23 $302,250.00 2,866 -6.67% view
S 2013-09-11 2013-09-11 19:26:58.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 1,985 $31.18 $61,894.30 956 -4.36% view
S 2013-09-11 2013-09-11 19:26:58.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 1,520 $31.18 $47,395.10 2,941 -4.36% view
S 2013-09-10 2013-09-11 19:26:58.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 30,000 $31.65 $949,440.00 2,941 -5.50% view
S 2013-09-09 2013-09-11 19:26:58.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 30,000 $30.42 $912,450.00 2,941 -6.00% view
S 2013-09-04 2013-09-06 19:04:09.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 10 $26.85 $268.50 2,023 -34.34% view
S 2013-09-04 2013-09-06 19:04:09.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 10 $26.85 $268.50 2,023 -34.34% view
S 2013-09-04 2013-09-06 19:04:09.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 637 $26.85 $17,103.40 2,023 -34.34% view
S 2013-09-04 2013-09-06 19:04:09.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 526 $27.00 $14,202.00 2,023 -33.59% view
S 2013-09-04 2013-09-06 19:04:09.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,317 $27.25 $35,888.20 2,023 -32.37% view
S 2013-08-26 2013-08-28 19:19:55.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 2,909 $25.58 $74,403.20 769 -48.73% view
S 2013-08-09 2013-08-13 19:45:39.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 7,500 $28.22 $211,650.00 8,313 -12.72% view
S 2013-08-09 2013-08-13 19:45:39.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 7,500 $28.22 $211,650.00 8,313 -12.72% view
S 2013-08-09 2013-08-13 19:45:39.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 3,647 $28.22 $102,918.00 8,313 -12.72% view
S 2013-08-09 2013-08-13 19:45:39.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 103 $28.23 $2,907.69 8,313 -12.68% view
S 2013-07-23 2013-07-25 20:19:28.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (COO, President) 11,500 $30.00 $345,000.00 1,661 14.53% view
S 2013-07-22 2013-07-22 19:52:25.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 1,885 $31.02 $58,472.70 1,661 17.12% view
S 2013-07-22 2013-07-22 19:52:25.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 8,115 $31.02 $251,727.00 1,661 17.12% view
S 2013-07-22 2013-07-22 19:52:25.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $30.52 $305,250.00 1,661 15.77% view
S 2013-07-19 2013-07-22 19:52:25.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $30.18 $301,850.00 1,661 16.32% view
S 2013-07-19 2013-07-22 19:52:25.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $30.87 $308,720.00 1,661 18.18% view
S 2013-07-19 2013-07-22 19:52:25.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 2,200 $31.40 $69,080.00 1,661 19.55% view
S 2013-07-18 2013-07-22 19:52:25.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $30.02 $300,220.00 1,661 16.16% view
S 2013-07-18 2013-07-22 19:52:25.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $30.20 $302,000.00 1,661 16.66% view
S 2013-07-17 2013-07-17 19:42:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 5,000 $31.96 $159,800.00 174 21.25% view
S 2013-07-17 2013-07-17 19:42:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 44 $31.96 $1,406.24 174 21.25% view
S 2013-07-17 2013-07-17 19:42:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 8,256 $31.22 $257,752.00 174 19.38% view
S 2013-07-16 2013-07-17 19:42:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 6,000 $33.31 $199,842.00 1,661 24.43% view
S 2013-07-15 2013-07-17 19:42:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $33.56 $335,650.00 1,661 22.63% view
S 2013-07-15 2013-07-17 19:42:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $33.81 $338,050.00 1,661 23.18% view
S 2013-07-15 2013-07-17 19:42:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $34.05 $340,480.00 1,661 23.73% view
S 2013-07-12 2013-07-12 19:45:23.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 12,000 $33.50 $402,010.00 1,661 18.96% view
S 2013-07-12 2013-07-12 19:45:23.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 12,000 $33.08 $397,008.00 1,661 17.94% view
S 2013-07-12 2013-07-12 19:45:23.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 6,000 $32.83 $196,980.00 1,661 17.30% view
S 2013-07-11 2013-07-12 19:45:23.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 30,000 $32.00 $960,090.00 1,661 11.85% view
S 2013-07-10 2013-07-12 19:45:23.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 30,000 $30.05 $901,440.00 1,661 6.12% view
S 2013-07-11 2013-07-12 19:44:32.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 9,000 $31.90 $287,100.00 3,446 11.57% view
S 2013-07-09 2013-07-09 20:36:25.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 10,358 $30.04 $311,185.00 3,446 6.10% view
S 2013-07-08 2013-07-09 20:36:25.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 7,060 $30.09 $212,435.00 3,446 6.58% view
S 2013-07-08 2013-07-09 20:36:25.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 17,933 $30.09 $539,604.00 3,446 6.58% view
S 2013-07-08 2013-07-09 20:36:25.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 5,007 $30.03 $150,340.00 3,446 6.38% view
S 2013-07-05 2013-07-09 20:36:25.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 5,000 $30.01 $150,075.00 3,446 4.55% view
S 2013-07-05 2013-07-09 20:36:25.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 2,220 $30.01 $66,633.30 3,446 4.55% view
S 2013-07-05 2013-07-09 20:36:25.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 16,960 $30.01 $509,054.00 3,446 4.55% view
S 2013-07-05 2013-07-09 20:36:25.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 1,625 $29.25 $47,531.20 3,446 2.05% view
S 2013-07-09 2013-07-09 19:39:38.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 30,000 $30.04 $901,290.00 1,661 6.10% view
S 2013-07-08 2013-07-09 19:39:38.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 24,992 $30.09 $752,009.00 1,661 6.58% view
S 2013-07-08 2013-07-09 19:39:38.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 24,992 $15.38 $384,377.00 26,653 -82.77% view
S 2013-07-08 2013-07-09 19:39:38.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 5,008 $30.03 $150,370.00 1,661 6.38% view
S 2013-07-05 2013-07-09 19:39:38.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 24,180 $30.01 $725,763.00 1,661 4.55% view
S 2013-07-05 2013-07-05 18:02:26.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 277 $29.25 $8,102.25 2,023 2.05% view
S 2013-07-03 2013-07-03 17:17:09.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 5,000 $29.02 $145,100.00 5,071 -0.72% view
S 2013-07-02 2013-07-03 17:15:54.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 215 $28.69 $6,169.40 5,842 -1.86% view
S 2013-07-01 2013-07-01 19:34:27.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $28.17 $281,700.00 775,391 -3.98% view
S 2013-06-28 2013-07-01 19:34:27.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 5,958 $27.31 $162,713.00 174 -6.08% view
S 2013-06-28 2013-07-01 19:34:27.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 4,725 $27.31 $129,040.00 174 -6.08% view
S 2013-06-28 2013-07-01 19:34:27.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $27.07 $270,700.00 1,661 -7.02% view
S 2013-06-27 2013-07-01 19:34:27.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $27.40 $274,000.00 1,661 -5.73% view
S 2013-06-27 2013-07-01 19:34:27.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $28.30 $283,000.00 1,661 -2.37% view
S 2013-06-26 2013-06-26 19:46:57.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,000 $26.70 $267,000.00 785,391 -8.50% view
S 2013-06-26 2013-06-26 19:46:57.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 20,000 $27.10 $542,020.00 1,661 -6.90% view
S 2013-06-25 2013-06-26 19:46:57.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 19,565 $27.86 $545,179.00 1,661 -5.04% view
S 2013-06-25 2013-06-26 19:46:57.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 10,435 $28.32 $295,519.00 1,661 -3.35% view
S 2013-06-24 2013-06-26 19:46:57.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 13,730 $25.22 $346,271.00 795,391 -13.05% view
S 2013-06-24 2013-06-26 19:46:57.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman and CEO) 16,270 $25.16 $409,353.00 809,121 -13.31% view
S 2013-06-25 2013-06-26 19:46:06.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 10,435 $27.86 $290,771.00 4,254 -5.04% view
S 2013-06-25 2013-06-26 19:46:06.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 1,565 $28.32 $44,320.80 4,254 -3.35% view
S 2013-06-25 2013-06-26 19:46:06.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 4,000 $28.32 $113,280.00 4,254 -3.35% view
S 2013-06-25 2013-06-26 19:46:06.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 1,049 $27.56 $28,910.40 4,254 -6.20% view
S 2013-06-24 2013-06-26 19:46:06.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 10,000 $25.16 $251,600.00 4,254 -13.31% view
S 2013-06-24 2013-06-26 19:46:06.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 6,270 $25.16 $157,753.00 4,254 -13.31% view
S 2013-06-24 2013-06-26 19:46:06.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 13,730 $25.22 $346,271.00 4,254 -13.05% view
S 2013-06-20 2013-06-24 20:34:36.0 ISIS PHARMACEUTICALS INC ISIS WENDER JOSEPH H director 5,447 $20.93 $114,006.00 55,553 -48.35% view
S 2013-05-30 2013-05-31 19:15:42.0 ISIS PHARMACEUTICALS INC ISIS MUTO FREDERICK T director 10,000 $21.96 $219,600.00 0 -22.36% view
S 2013-05-01 2013-05-02 19:48:50.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 6,145 $22.26 $136,794.00 2,110 2.57% view
S 2013-05-01 2013-05-02 19:48:50.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 23,800 $22.26 $529,812.00 2,110 2.57% view
S 2013-04-30 2013-05-02 19:48:50.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 30,000 $22.51 $675,153.00 2,110 3.18% view
S 2013-04-25 2013-04-26 19:06:49.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 18,400 $22.50 $413,908.00 2,941 6.73% view
S 2013-04-25 2013-04-26 19:06:49.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 7,454 $22.50 $167,678.00 2,941 6.73% view
S 2013-04-24 2013-04-26 19:06:49.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 30,000 $22.12 $663,600.00 2,941 5.15% view
S 2013-04-24 2013-04-26 19:03:12.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 10,417 $22.38 $233,132.00 300 6.26% view
S 2013-04-24 2013-04-26 19:02:22.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 10,000 $22.12 $221,200.00 825,391 5.15% view
S 2013-04-23 2013-04-23 21:05:40.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 3,900 $22.13 $86,307.00 1,324 6.73% view
S 2013-04-23 2013-04-23 21:05:40.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,800 $22.13 $39,834.00 1,324 6.73% view
S 2013-04-23 2013-04-23 21:05:40.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 2,700 $22.13 $59,751.00 1,324 6.73% view
S 2013-04-23 2013-04-23 21:05:40.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 2,260 $22.13 $50,013.80 1,324 6.73% view
S 2013-04-23 2013-04-23 21:05:40.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 10,660 $22.13 $235,906.00 1,324 6.73% view
S 2013-04-23 2013-04-23 21:05:40.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 6,000 $22.13 $132,780.00 1,324 6.73% view
S 2013-04-19 2013-04-23 21:05:40.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 5,000 $21.01 $105,050.00 1,324 1.67% view
S 2013-04-19 2013-04-23 21:05:40.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 6,000 $20.01 $120,036.00 1,324 -3.27% view
S 2013-04-19 2013-04-23 21:05:40.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,000 $19.60 $19,600.00 1,324 -5.41% view
S 2013-04-19 2013-04-23 21:05:40.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 3,000 $20.25 $60,750.00 1,324 -2.02% view
S 2013-04-23 2013-04-23 20:49:33.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 10,000 $22.10 $220,967.00 0 6.59% view
S 2013-04-23 2013-04-23 20:49:33.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 10,000 $22.10 $220,967.00 0 6.59% view
S 2013-04-23 2013-04-23 20:49:33.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 10,000 $22.10 $220,967.00 2,941 6.59% view
S 2013-04-22 2013-04-23 20:49:33.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 30,000 $20.99 $629,700.00 2,941 2.86% view
S 2013-04-19 2013-04-23 20:49:33.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 30,000 $20.01 $600,180.00 2,941 -3.27% view
S 2013-04-22 2013-04-23 20:48:25.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 17,000 $21.26 $361,420.00 5,695 4.09% view
S 2013-04-19 2013-04-23 20:48:25.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 2,500 $21.25 $53,125.00 5,695 2.78% view
S 2013-04-23 2013-04-23 20:47:27.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 30,000 $22.10 $662,901.00 835,391 6.59% view
S 2013-04-22 2013-04-23 20:47:27.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 10,000 $20.99 $209,900.00 865,391 2.86% view
S 2013-04-22 2013-04-23 20:47:27.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 20,000 $20.99 $419,800.00 1,661 2.86% view
S 2013-04-19 2013-04-23 20:47:27.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 30,000 $20.01 $600,180.00 1,661 -3.27% view
S 2013-04-22 2013-04-23 20:46:45.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 2,000 $21.43 $42,860.00 300 4.85% view
S 2013-04-22 2013-04-23 20:46:45.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 3,000 $21.41 $64,230.00 300 4.76% view
S 2013-04-22 2013-04-23 20:46:45.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 2,813 $21.40 $60,198.20 300 4.72% view
S 2013-04-22 2013-04-23 20:46:45.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 9,843 $21.49 $211,526.00 300 5.12% view
S 2013-04-19 2013-04-23 20:45:34.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 2,042 $20.80 $42,473.60 4,254 0.67% view
S 2013-04-12 2013-04-15 19:10:11.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 4,330 $19.62 $84,947.70 1,324 3.05% view
S 2013-04-12 2013-04-15 19:10:11.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 1,130 $19.60 $22,148.00 1,324 2.96% view
S 2013-04-11 2013-04-15 19:08:54.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Sr VP, Development) 7,000 $19.52 $136,640.00 4,254 2.56% view
S 2013-03-21 2013-03-22 19:58:15.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Sr VP, Development) 1,000 $19.50 $19,500.00 4,254 -8.21% view
S 2013-03-21 2013-03-22 19:57:14.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 9,000 $19.26 $173,340.00 1,324 -9.55% view
S 2013-03-20 2013-03-21 20:26:11.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance and CFO) 4,792 $18.13 $86,879.00 300 -16.38% view
S 2013-03-20 2013-03-21 20:26:11.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance and CFO) 9,584 $18.13 $173,758.00 300 -16.38% view
S 2013-03-20 2013-03-21 20:25:43.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 174 $18.00 $3,132.00 0 -17.22% view
S 2013-03-20 2013-03-21 20:25:43.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 1,250 $18.00 $22,500.00 0 -17.22% view
S 2013-03-20 2013-03-21 20:25:43.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 2,500 $18.00 $45,000.00 0 -17.22% view
S 2013-03-13 2013-03-14 21:01:29.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 6,667 $18.01 $120,052.00 0 -6.57% view
S 2013-03-13 2013-03-14 21:01:29.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 266 $18.01 $4,789.84 0 -6.57% view
S 2013-03-13 2013-03-14 21:01:29.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 6,667 $18.01 $120,052.00 0 -6.57% view
S 2013-03-13 2013-03-14 21:01:29.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 266 $18.01 $4,789.84 0 -6.57% view
S 2013-03-13 2013-03-14 21:01:29.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 6,666 $18.01 $120,034.00 100 -6.57% view
S 2013-03-13 2013-03-14 21:01:29.0 ISIS PHARMACEUTICALS INC ISIS KLEIN JOSEPH III director 268 $18.01 $4,825.85 100 -6.57% view
S 2013-03-05 2013-03-07 20:17:23.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance and CFO) 5,040 $16.86 $84,959.80 300 -2.86% view
S 2013-03-05 2013-03-07 20:16:53.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 18,240 $16.86 $307,599.00 5,695 -2.82% view
S 2013-03-04 2013-03-04 20:06:21.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 1,350 $15.82 $21,352.90 1,324 -6.15% view
S 2013-03-04 2013-03-04 20:06:21.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 10,350 $15.82 $163,706.00 1,324 -6.15% view
S 2013-02-19 2013-02-20 19:04:24.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 1,600 $14.80 $23,680.00 1,324 -18.65% view
S 2013-02-15 2013-02-20 19:04:24.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 250 $14.82 $3,705.00 1,324 -19.16% view
S 2013-02-15 2013-02-20 19:04:24.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 100 $14.80 $1,480.00 1,324 -19.32% view
S 2013-02-13 2013-02-14 20:36:03.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 139 $14.17 $1,969.63 1,324 -24.63% view
S 2013-02-13 2013-02-14 20:36:03.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 5,200 $14.17 $73,684.00 1,463 -24.63% view
S 2013-02-13 2013-02-14 20:36:03.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 900 $14.17 $12,753.00 1,463 -24.63% view
S 2013-01-30 2013-01-31 19:58:28.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 2,000 $14.82 $29,640.00 1,463 0.81% view
S 2013-01-29 2013-01-31 19:58:28.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 300 $13.40 $4,020.00 1,463 -9.70% view
S 2013-01-17 2013-01-17 20:49:06.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal & General Counsel) 242 $14.16 $3,426.72 1,763 -1.91% view
S 2013-01-16 2013-01-17 20:49:06.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 759 $14.00 $10,626.00 2,941 -3.07% view
S 2013-01-16 2013-01-17 20:49:05.0 ISIS PHARMACEUTICALS INC ISIS HOUGEN ELIZABETH L officer (SVP, Finance & CFO) 242 $14.00 $3,388.00 300 -3.07% view
S 2013-01-16 2013-01-17 20:49:05.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 95 $14.00 $1,330.00 5,695 -3.07% view
S 2013-01-16 2013-01-17 20:49:05.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 235 $14.00 $3,290.00 5,581 -3.07% view
S 2013-01-16 2013-01-17 20:49:05.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 143 $14.00 $2,001.91 174 -3.08% view
S 2013-01-16 2013-01-17 20:49:05.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 1,317 $14.00 $18,437.90 1,661 -3.07% view
S 2013-01-16 2013-01-17 20:49:05.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (SVP, Development) 345 $14.00 $4,830.00 4,254 -3.07% view
S 2013-01-16 2013-01-17 20:49:05.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 309 $14.00 $4,326.00 2,110 -3.07% view
S 2013-01-04 2013-01-04 20:01:21.0 ISIS PHARMACEUTICALS INC ISIS O'NEIL PATRICK R. officer (SVP, Legal and General Counsel) 1,296 $10.76 $13,945.00 1,463 -34.39% view
S 2013-01-03 2013-01-03 19:47:05.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (VP, Antisense Drug Discovery) 311 $10.84 $3,371.24 5,288 -35.89% view
S 2013-01-03 2013-01-03 19:44:53.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Sr VP, Development) 265 $10.84 $2,872.60 3,823 -35.89% view
S 2012-12-13 2012-12-17 20:04:28.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Sr VP, Development) 6,000 $9.63 $57,750.60 3,190 -37.97% view
S 2012-09-21 2012-09-21 19:21:12.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 29,462 $14.06 $414,236.00 0 33.50% view
S 2012-09-20 2012-09-21 19:21:12.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 20,538 $15.01 $308,234.00 0 37.70% view
S 2012-09-20 2012-09-21 19:21:12.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 9,462 $15.01 $142,006.00 0 37.70% view
S 2012-09-19 2012-09-21 19:21:12.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 30,000 $14.81 $444,450.00 0 36.89% view
S 2012-09-13 2012-09-17 18:36:54.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 27,074 $14.55 $393,927.00 0 13.13% view
S 2012-09-07 2012-09-11 18:32:43.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 5,000 $15.12 $75,600.00 0 17.39% view
S 2012-09-07 2012-09-11 18:32:43.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 5,000 $15.12 $75,600.00 0 17.39% view
S 2012-09-07 2012-09-11 18:32:43.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 2,506 $15.12 $37,890.70 1,985 17.39% view
S 2012-09-06 2012-09-06 21:49:54.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 5,000 $15.00 $75,010.00 0 16.74% view
S 2012-09-06 2012-09-06 21:49:54.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 5,000 $15.03 $75,175.00 0 16.93% view
S 2012-09-06 2012-09-06 21:49:54.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 5,000 $15.00 $75,010.00 0 16.74% view
S 2012-09-06 2012-09-06 21:49:54.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 5,000 $15.03 $75,175.00 0 16.93% view
S 2012-09-06 2012-09-06 21:49:54.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 5,000 $15.00 $75,010.00 1,985 16.74% view
S 2012-09-06 2012-09-06 21:49:54.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 2,506 $15.03 $37,677.70 1,985 16.93% view
S 2012-09-06 2012-09-06 21:49:54.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 2,494 $15.03 $37,497.30 1,985 16.93% view
S 2012-09-05 2012-09-06 21:49:54.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 2,000 $15.00 $30,000.00 1,985 16.73% view
S 2012-09-04 2012-09-06 21:49:54.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 10,000 $15.00 $150,010.00 0 16.01% view
S 2012-09-04 2012-09-06 21:49:54.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 10,000 $15.00 $150,010.00 0 16.01% view
S 2012-09-04 2012-09-06 21:49:54.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO, Secretary) 10,000 $15.00 $150,010.00 1,985 16.01% view
S 2012-09-06 2012-09-06 21:40:30.0 ISIS PHARMACEUTICALS INC ISIS REED JOHN C director 4,900 $15.18 $74,357.50 0 17.69% view
S 2012-09-04 2012-09-06 21:40:30.0 ISIS PHARMACEUTICALS INC ISIS REED JOHN C director 5,100 $15.17 $77,367.00 0 16.94% view
S 2012-09-06 2012-09-06 21:39:11.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 6,000 $15.00 $90,012.00 0 16.74% view
S 2012-09-06 2012-09-06 21:39:11.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 306 $15.00 $4,590.61 0 16.74% view
S 2012-09-06 2012-09-06 21:39:11.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 4,381 $15.03 $65,868.30 0 16.93% view
S 2012-09-06 2012-09-06 21:39:11.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 1,925 $15.03 $28,942.40 0 16.93% view
S 2012-09-06 2012-09-06 21:39:10.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 8,694 $15.03 $130,714.00 0 16.93% view
S 2012-09-06 2012-09-06 21:39:10.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 8,694 $15.00 $130,427.00 0 16.74% view
S 2012-09-05 2012-09-06 21:39:10.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 15,000 $14.82 $222,345.00 0 15.74% view
S 2012-09-04 2012-09-06 21:39:10.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, CEO and President) 30,000 $14.11 $423,255.00 0 10.69% view
S 2012-07-09 2012-07-11 16:47:29.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 5,000 $13.51 $67,550.00 1,277 4.74% view
S 2012-07-09 2012-07-11 16:47:29.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 5,500 $13.51 $74,305.00 1,277 4.74% view
S 2012-07-09 2012-07-11 16:46:29.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Sr VP, Development) 1,000 $13.45 $13,450.00 3,190 4.31% view
S 2012-07-09 2012-07-11 16:46:29.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Sr VP, Development) 2,000 $13.49 $26,980.00 3,190 4.60% view
S 2012-07-09 2012-07-11 16:46:29.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Sr VP, Development) 2,686 $13.47 $36,180.40 3,190 4.45% view
S 2012-07-09 2012-07-11 16:43:48.0 ISIS PHARMACEUTICALS INC ISIS REED JOHN C director 10,000 $13.99 $139,900.00 0 8.01% view
S 2012-07-03 2012-07-03 19:07:29.0 ISIS PHARMACEUTICALS INC ISIS Monia Brett P officer (SVP, Antisense Drug Discovery) 587 $12.92 $7,584.04 5,384 6.50% view
S 2012-07-03 2012-07-03 19:06:47.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (SVP, Antisense Research) 6,000 $12.91 $77,460.00 1,277 6.43% view
S 2012-07-03 2012-07-03 19:06:14.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Sr VP, Development) 2,434 $12.91 $31,422.90 3,190 6.43% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 172 $11.62 $1,998.64 29,300 -7.40% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 1,600 $11.60 $18,560.00 29,300 -7.59% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 100 $11.59 $1,159.00 29,300 -7.68% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 1,500 $11.58 $17,373.00 29,300 -7.75% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 3,500 $11.58 $40,530.00 29,300 -7.77% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 700 $11.56 $8,092.00 29,300 -7.96% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 495 $11.55 $5,717.25 29,300 -8.05% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 205 $11.54 $2,365.70 29,300 -8.15% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 228 $11.53 $2,628.84 29,300 -8.24% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 500 $11.51 $5,755.00 29,300 -8.43% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 200 $11.50 $2,300.00 29,300 -8.52% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 300 $11.49 $3,447.90 29,300 -8.59% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 200 $11.49 $2,298.00 29,300 -8.62% view
S 2012-06-25 2012-06-25 20:57:37.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 300 $11.48 $3,444.00 29,300 -8.71% view
S 2012-06-14 2012-06-14 20:16:47.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Sr VP, Development) 1,579 $10.86 $17,147.90 4,324 -23.48% view
S 2012-05-22 2012-05-22 19:51:55.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 17,269 $9.56 $165,092.00 29,300 -24.37% view
S 2012-05-21 2012-05-22 19:51:55.0 ISIS PHARMACEUTICALS INC ISIS BERTHELSEN SPENCER R director 2,731 $9.42 $25,726.00 29,300 -15.39% view
S 2011-12-21 2011-12-22 17:22:33.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Senior Vice President) 1,144 $6.92 $7,916.48 4,278 -14.16% view
S 2011-12-21 2011-12-22 17:21:50.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 1,080 $6.92 $7,473.60 0 -14.16% view
S 2011-12-21 2011-12-22 17:21:50.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 16,720 $6.92 $115,702.00 0 -14.16% view
S 2011-12-21 2011-12-22 17:21:27.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,200 $6.92 $15,224.00 0 -14.16% view
S 2011-12-21 2011-12-22 17:21:27.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,200 $6.92 $15,224.00 0 -14.16% view
S 2011-12-21 2011-12-22 17:21:27.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,363 $6.92 $16,352.00 1,985 -14.16% view
S 2011-12-21 2011-12-22 17:20:54.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 1,555 $6.92 $10,760.60 305 -14.16% view
S 2011-12-20 2011-12-20 21:10:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 1,400 $6.82 $9,548.00 0 -15.84% view
S 2011-12-20 2011-12-20 21:10:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 300 $6.92 $2,076.00 0 -14.16% view
S 2011-12-20 2011-12-20 21:10:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 5,000 $6.92 $34,600.00 0 -14.16% view
S 2011-12-20 2011-12-20 21:10:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 22,000 $6.82 $150,040.00 0 -15.84% view
S 2011-12-19 2011-12-20 21:10:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 982 $6.82 $6,697.24 0 -17.30% view
S 2011-12-19 2011-12-20 21:10:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 118 $6.90 $814.20 0 -15.94% view
S 2011-12-19 2011-12-20 21:10:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 15,178 $6.82 $103,514.00 0 -17.30% view
S 2011-12-19 2011-12-20 21:10:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 1,822 $6.90 $12,571.80 0 -15.94% view
S 2011-12-16 2011-12-20 21:10:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 1,500 $6.79 $10,185.00 0 -11.93% view
S 2011-12-16 2011-12-20 21:10:00.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 15,000 $6.79 $101,850.00 0 -11.93% view
S 2011-12-20 2011-12-20 21:08:47.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 500 $6.92 $3,460.00 305 -14.16% view
S 2011-12-20 2011-12-20 21:08:47.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 2,000 $6.82 $13,640.00 305 -15.84% view
S 2011-12-19 2011-12-20 21:08:47.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 1,340 $6.82 $9,138.80 305 -17.30% view
S 2011-12-19 2011-12-20 21:08:47.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 160 $6.90 $1,104.00 305 -15.94% view
S 2011-12-16 2011-12-20 21:08:47.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 1,500 $6.79 $10,185.00 305 -11.93% view
S 2011-12-20 2011-12-20 21:07:05.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Senior Vice President) 300 $6.92 $2,076.00 4,278 -14.16% view
S 2011-12-20 2011-12-20 21:07:05.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Senior Vice President) 1,500 $6.82 $10,230.00 4,278 -15.84% view
S 2011-12-19 2011-12-20 21:07:05.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Senior Vice President) 982 $6.82 $6,697.24 4,278 -17.30% view
S 2011-12-19 2011-12-20 21:07:05.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Senior Vice President) 118 $6.90 $814.20 4,278 -15.94% view
S 2011-12-16 2011-12-20 21:07:05.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Senior Vice President) 1,000 $6.79 $6,790.00 4,278 -11.93% view
S 2011-12-19 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,054 $6.82 $14,008.30 0 -17.30% view
S 2011-12-19 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 246 $6.90 $1,697.40 0 -15.94% view
S 2011-12-20 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,800 $6.82 $19,096.00 0 -15.84% view
S 2011-12-20 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 700 $6.92 $4,844.00 0 -14.16% view
S 2011-12-20 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,800 $6.82 $19,096.00 0 -15.84% view
S 2011-12-20 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 700 $6.92 $4,844.00 0 -14.16% view
S 2011-12-20 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 700 $6.92 $4,844.00 1,985 -14.16% view
S 2011-12-20 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,900 $6.82 $19,778.00 1,985 -15.84% view
S 2011-12-19 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 246 $6.90 $1,697.40 0 -15.94% view
S 2011-12-19 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,054 $6.82 $14,008.30 0 -17.30% view
S 2011-12-19 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 246 $6.90 $1,697.40 1,985 -15.94% view
S 2011-12-19 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,054 $6.82 $14,008.30 1,985 -17.30% view
S 2011-12-16 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,000 $6.79 $13,580.00 0 -11.93% view
S 2011-12-16 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,000 $6.79 $13,580.00 0 -11.93% view
S 2011-12-16 2011-12-20 21:06:45.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 2,000 $6.79 $13,580.00 1,985 -11.93% view
S 2011-08-04 2011-08-05 17:42:02.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 10,000 $7.62 $76,206.00 305 8.80% view
S 2011-07-28 2011-07-29 18:12:23.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 1,000 $8.60 $8,600.00 305 17.21% view
S 2010-12-29 2010-12-29 20:16:06.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Senior Vice President) 1,980 $10.31 $20,423.70 1,579 12.36% view
S 2010-12-27 2010-12-29 20:16:06.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Senior Vice President) 3,300 $10.42 $34,386.00 1,579 8.45% view
S 2010-12-29 2010-12-29 20:15:13.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 6,400 $10.31 $66,016.00 1,985 12.36% view
S 2010-12-27 2010-12-29 20:15:13.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 10,800 $10.42 $112,536.00 1,985 8.45% view
S 2010-12-29 2010-12-29 20:10:38.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 4,600 $10.31 $47,449.00 561 12.36% view
S 2010-12-27 2010-12-29 20:10:38.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 7,700 $10.42 $80,234.00 561 8.45% view
S 2010-12-29 2010-12-29 19:23:52.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 2,000 $10.31 $20,630.00 0 12.36% view
S 2010-12-29 2010-12-29 19:23:52.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 10,000 $10.31 $103,150.00 0 12.36% view
S 2010-12-27 2010-12-29 19:23:52.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 20,000 $10.42 $208,400.00 0 8.45% view
S 2010-12-23 2010-12-28 19:41:54.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Senior Vice President) 200 $10.52 $2,105.00 1,579 11.92% view
S 2010-12-23 2010-12-27 16:11:09.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 800 $10.52 $8,420.00 1,985 11.92% view
S 2010-12-23 2010-12-27 16:11:09.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 650 $10.52 $6,841.25 0 11.92% view
S 2010-12-23 2010-12-27 16:11:09.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 650 $10.52 $6,841.25 0 11.92% view
S 2010-12-22 2010-12-27 16:11:09.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (COO) 4,350 $10.52 $45,762.00 0 11.88% view
S 2010-12-23 2010-12-27 16:10:25.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Senior Vice President) 400 $10.52 $4,210.00 1,579 11.92% view
S 2010-12-22 2010-12-27 16:10:25.0 ISIS PHARMACEUTICALS INC ISIS Geary Richard S officer (Senior Vice President) 2,600 $10.52 $27,352.00 1,579 11.88% view
S 2010-12-23 2010-12-27 16:10:12.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 4,000 $10.52 $42,100.00 0 11.92% view
S 2010-12-22 2010-12-27 16:10:12.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 16,000 $10.52 $168,320.00 0 11.88% view
S 2010-12-23 2010-12-27 16:10:12.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 1,500 $10.52 $15,787.50 561 11.92% view
S 2010-12-22 2010-12-27 16:10:12.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 6,200 $10.52 $65,224.00 561 11.88% view
S 2010-07-23 2010-07-26 16:35:48.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 1,100 $9.60 $10,560.00 561 18.96% view
S 2010-06-30 2010-06-30 19:48:13.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 1,000 $9.75 $9,750.00 1,171 -1.44% view
S 2010-06-29 2010-06-30 19:48:13.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 3,000 $9.71 $29,139.90 1,171 -0.79% view
S 2010-06-28 2010-06-30 19:48:13.0 ISIS PHARMACEUTICALS INC ISIS BENNETT C FRANK officer (Senior Vice President) 6,000 $10.01 $60,060.00 1,171 3.20% view
S 2009-12-31 2009-12-31 16:41:55.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 3,545 $11.21 $39,739.40 0 0.45% view
S 2009-12-31 2009-12-31 16:41:55.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 3,545 $11.21 $39,739.40 0 0.45% view
S 2009-12-30 2009-12-30 19:54:57.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 3,000 $11.06 $33,195.00 0 -0.86% view
S 2009-12-30 2009-12-30 19:54:57.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 3,000 $11.06 $33,195.00 0 -0.86% view
S 2009-12-28 2009-12-30 19:54:57.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 1,000 $11.17 $11,170.00 0 -0.90% view
S 2009-12-28 2009-12-30 19:54:57.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 1,000 $11.17 $11,170.00 0 -0.90% view
S 2009-12-30 2009-12-30 19:53:58.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 6,535 $11.06 $72,309.80 0 -0.86% view
S 2009-12-22 2009-12-23 17:40:04.0 ISIS PHARMACEUTICALS INC ISIS CROOKE STANLEY T director officer (Chairman, President, CEO) 20,000 $10.13 $202,600.00 0 -10.07% view
S 2009-12-23 2009-12-23 17:39:10.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 7,500 $10.59 $79,425.00 0 -5.29% view
S 2009-12-23 2009-12-23 17:39:10.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 7,500 $10.59 $79,425.00 0 -5.29% view
S 2009-12-23 2009-12-23 17:39:10.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 1,910 $10.59 $20,226.90 1,985 -5.29% view
S 2009-12-22 2009-12-23 17:39:10.0 ISIS PHARMACEUTICALS INC ISIS PARSHALL B LYNNE director officer (Director, COO) 10,000 $10.13 $101,300.00 1,985 -10.07% view
* An * after P or S in the Buy/Sell column means the transaction was filed by the insider as open market, but it was marked as private transaction by insidercow's proprietary method
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